Programmable N6-methyladenosine modification of CDCP1 mRNA by RCas9-methyltransferase like 3 conjugates promotes bladder cancer development

Accumulating evidence has revealed significant roles for N6-methyladenosine (m 6 A) modification in the development of various cancers. We previously demonstrated an oncogenic role of m 6 A-modified CUB domain containing protein 1 (CDCP1) in bladder cancer (BC) progression. However, the biological f...

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Publicat a:Mol Cancer
Autors principals: Ying, Xiaoling, Jiang, Xu, Zhang, Haiqing, Liu, Bixia, Huang, Yapeng, Zhu, Xiaowei, Qi, Defeng, Yuan, Gang, Luo, Junhang, Ji, Weidong
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Letter to the Editor
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7712571/
https://ncbi.nlm.nih.gov/pubmed/33267838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-020-01289-0
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