Epitranscriptomic editing of the RNA N6-methyladenosine modification by dCasRx conjugated methyltransferase and demethylase

N6-methyladenosine (m6A) is a common modification on endogenous RNA transcripts in mammalian cells. Technologies to precisely modify the RNA m6A levels at specific transcriptomic loci empower interrogation of biological functions of epitranscriptomic modifications. Here, we developed a bidirectional...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Xia, Zhen, Tang, Min, Ma, Jiayan, Zhang, Hongyan, Gimple, Ryan C, Prager, Briana C, Tang, Hongzhen, Sun, Chongran, Liu, Fuyi, Lin, Peng, Mei, Yutang, Du, Ruoxin, Rich, Jeremy N, Xie, Qi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2021
Soggetti:
Gene regulation, Chromatin and Epigenetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287920/
https://ncbi.nlm.nih.gov/pubmed/34181729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab517
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi