Dynamic m(6)A mRNA methylation reveals the role of METTL3-m(6)A-CDCP1 signaling axis in chemical carcinogenesis

N6-methyladenosine (m(6)A) is the most abundant internal modification in mammalian mRNAs. Despite its functional importance in various physiological events, the role of m(6)A in chemical carcinogenesis remains largely unknown. Here we profiled the dynamic m(6)A mRNA modification during cellular tran...

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Vydáno v:Oncogene
Hlavní autoři: Yang, Fan, Jin, Huan, Que, Biao, Chao, Yinghui, Zhang, Haiqing, Ying, Xiaoling, Zhou, Zhongyang, Yuan, Zusen, Su, Jialin, Wu, Bin, Zhang, Wenjuan, Qi, Defeng, Chen, Demeng, Min, Wang, Lin, Shuibin, Ji, Weidong
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756049/
https://ncbi.nlm.nih.gov/pubmed/30796352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-019-0755-0
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