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Combinatorial Metabolic Engineering in Saccharomyces cerevisiae for the Enhanced Production of the FPP-Derived Sesquiterpene Germacrene

Farnesyl diphosphate (FPP)-derived isoprenoids represent a diverse group of plant secondary metabolites with great economic potential. To enable their efficient production in the heterologous host Saccharomyces cerevisiae, we refined a metabolic engineering strategy using the CRISPR/Cas9 system with...

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Bibliografiske detaljer
Udgivet i:Bioengineering (Basel)
Main Authors: Bröker, Jan Niklas, Müller, Boje, Prüfer, Dirk, Schulze Gronover, Christian
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7712416/
https://ncbi.nlm.nih.gov/pubmed/33114339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/bioengineering7040135
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