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Engineering Saccharomyces cerevisiae for geranylgeraniol overproduction by combinatorial design

Combinatorial design is an effective strategy to acquire the optimal solution in complex systems. In this study, the combined effects of pathway combination, promoters’ strength fine-tuning, copy numbers and integration locus variations caused by δ-integration were explored in Saccharomyces cerevisi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Song, Tian-Qing, Ding, Ming-Zhu, Zhai, Fang, Liu, Duo, Liu, Hong, Xiao, Wen-Hai, Yuan, Ying-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5678108/
https://ncbi.nlm.nih.gov/pubmed/29118396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15005-4
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