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Structural and functional interactions of the prostate cancer suppressor protein NKX3.1 with topoisomerase I

NKX3.1 (NK3 homeobox 1) is a prostate tumour suppressor protein with a number of activities that are critical for its role in tumour suppression. NKX3.1 mediates the cellular response to DNA damage by interacting with ATM (ataxia telangiectasia mutated) and by activation of topoisomerase I. In the p...

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Bibliografski detalji
Izdano u:Biochem J
Glavni autori: Song, Liang-Nian, Bowen, Cai, Gelmann, Edward P.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7711313/
https://ncbi.nlm.nih.gov/pubmed/23557481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20130012
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