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The Tumor Suppressor NKX3.1 is Targeted for Degradation by DYRK1B Kinase

NKX3.1 is a prostate specific homeodomain protein and tumor suppressor whose expression is reduced in the earliest phases of prostatic neoplasia. NKX3.1 expression is not only diminished by genetic loss and methylation, but the protein itself is a target for accelerated degradation caused by inflamm...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cancer Res
Egile Nagusiak: Song, Liang-Nian, Silva, Jose, Koller, Antonius, Rosenthal, Andrew, Chen, Emily I., Gelmann, Edward P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511920/
https://ncbi.nlm.nih.gov/pubmed/25777618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-14-0680
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