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Proline-mediated Proteasomal Degradation of the Prostate-specific Tumor Suppressor NKX3.1
Reduced expression of the homeodomain transcription factor NKX3.1 is associated with prostate cancer initiation and progression. NKX3.1 turnover requires post-translational modifications including phosphorylation and ubiquitination. Here, we demonstrate the existence of a non-canonical mechanism for...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3476300/ https://ncbi.nlm.nih.gov/pubmed/22910912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.352823 |
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