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Heparanase-enhanced Shedding of Syndecan-1 and Its Role in Driving Disease Pathogenesis and Progression

Both heparanase and syndecan-1 are known to be present and active in disease pathobiology. An important feature of syndecan-1 related to its role in pathologies is that it can be shed from the surface of cells as an intact ectodomain composed of the extracellular core protein and attached heparan su...

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Библиографические подробности
Опубликовано в: :J Histochem Cytochem
Главные авторы: Rangarajan, Sunil, Richter, Jillian R., Richter, Robert P., Bandari, Shyam K., Tripathi, Kaushlendra, Vlodavsky, Israel, Sanderson, Ralph D.
Формат: Artigo
Язык:Inglês
Опубликовано: SAGE Publications 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7711244/
https://ncbi.nlm.nih.gov/pubmed/32623935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/0022155420937087
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