A proof of concept ‘phase zero’ study of neurodevelopment using brain organoid models with Vis/near-infrared spectroscopy and electrophysiology

Homeostatic control of neuronal excitability by modulation of synaptic inhibition (I) and excitation (E) of the principal neurons is important during brain maturation. The fundamental features of in-utero brain development, including local synaptic E–I ratio and bioenergetics, can be modeled by cere...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dutta, Anirban, Karanth, Sneha Sudhakar, Bhattacharya, Mahasweta, Liput, Michal, Augustyniak, Justyna, Cheung, Mancheung, Stachowiak, Ewa K., Stachowiak, Michal K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710726/
https://ncbi.nlm.nih.gov/pubmed/33268815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77929-8
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