Bone marrow Tregs mediate stromal cell function and support hematopoiesis via IL-10

The nonimmune roles of Tregs have been described in various tissues, including the BM. In this study, we comprehensively phenotyped marrow Tregs, elucidating their key features and tissue-specific functions. We show that marrow Tregs are migratory and home back to the marrow. For trafficking, marrow...

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Pubblicato in:JCI Insight
Autori principali: Camacho, Virginia, Matkins, Victoria R., Patel, Sweta B., Lever, Jeremie M., Yang, Zhengqin, Ying, Li, Landuyt, Ashley E., Dean, Emma C., George, James F., Yang, Henry, Ferrell, Paul Brent, Maynard, Craig L., Weaver, Casey T., Turnquist, Heth R., Welner, Robert S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710301/
https://ncbi.nlm.nih.gov/pubmed/33208555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.135681
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