Direct modulation of the bone marrow mesenchymal stromal cell compartment by azacitidine enhances healthy hematopoiesis

Mesenchymal stromal cells (MSCs) are crucial components of the bone marrow (BM) microenvironment essential for regulating self-renewal, survival, and differentiation of hematopoietic stem/progenitor cells (HSPCs) in the stem cell niche. MSCs are functionally altered in myelodysplastic syndromes (MDS...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Blood Adv
Auteurs principaux: Wenk, Catharina, Garz, Anne-Kathrin, Grath, Sonja, Huberle, Christina, Witham, Denis, Weickert, Marie, Malinverni, Roberto, Niggemeyer, Julia, Kyncl, Michèle, Hecker, Judith, Pagel, Charlotta, Mulholland, Christopher B., Müller-Thomas, Catharina, Leonhardt, Heinrich, Bassermann, Florian, Oostendorp, Robert A. J., Metzeler, Klaus H., Buschbeck, Marcus, Götze, Katharina S.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2018
Sujets:
Myeloid Neoplasia
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290099/
https://ncbi.nlm.nih.gov/pubmed/30518537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018022053
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires