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Tumor genotype, location, and malignant potential shape the immunogenicity of primary untreated gastrointestinal stromal tumors

Intratumoral immune infiltrate was recently reported in gastrointestinal stromal tumors (GISTs). However, the tumor-intrinsic factors that dictate GIST immunogenicity are still largely undefined. To shed light on this issue, a large cohort (82 samples) of primary untreated GISTs, representative of m...

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Veröffentlicht in:JCI Insight
Hauptverfasser: Gasparotto, Daniela, Sbaraglia, Marta, Rossi, Sabrina, Baldazzi, Davide, Brenca, Monica, Mondello, Alessia, Nardi, Federica, Racanelli, Dominga, Cacciatore, Matilde, Paolo Dei Tos, Angelo, Maestro, Roberta
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710278/
https://ncbi.nlm.nih.gov/pubmed/33048845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.142560
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