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The co-existence of transcriptional activator and transcriptional repressor MEF2 complexes influences tumor aggressiveness
The contribution of MEF2 TFs to the tumorigenic process is still mysterious. Here we clarify that MEF2 can support both pro-oncogenic or tumor suppressive activities depending on the interaction with co-activators or co-repressors partners. Through these interactions MEF2 supervise histone modificat...
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| Publicado no: | PLoS Genet |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5413110/ https://ncbi.nlm.nih.gov/pubmed/28419090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006752 |
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