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Metformin delays neurological symptom onset in a mouse model of neuronal complex I deficiency
Complex I (also known as NADH-ubiquinone oxidoreductase) deficiency is the most frequent mitochondrial disorder present in childhood. NADH-ubiquinone oxidoreductase iron-sulfur protein 3 (NDUFS3) is a catalytic subunit of the mitochondrial complex I; NDUFS3 is conserved from bacteria and essential f...
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| Publicado en: | JCI Insight |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7710273/ https://ncbi.nlm.nih.gov/pubmed/33148885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.141183 |
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