Adipose‐derived mesenchymal stem cells reduce autophagy in stroke mice by extracellular vesicle transfer of miR‐25

Grafted mesenchymal stem cells (MSCs) yield neuroprotection in preclinical stroke models by secreting extracellular vesicles (EVs). The neuroprotective cargo of EVs, however, has not yet been identified. To investigate such cargo and its underlying mechanism, primary neurons were exposed to oxygen‐g...

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Veröffentlicht in:J Extracell Vesicles
Hauptverfasser: Kuang, Yaoyun, Zheng, Xuan, Zhang, Lin, Ai, Xiaoyu, Venkataramani, Vivek, Kilic, Ertugrul, Hermann, Dirk M., Majid, Arshad, Bähr, Mathias, Doeppner, Thorsten R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710129/
https://ncbi.nlm.nih.gov/pubmed/33304476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jev2.12024
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