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Adipose‐derived mesenchymal stem cells reduce autophagy in stroke mice by extracellular vesicle transfer of miR‐25

Grafted mesenchymal stem cells (MSCs) yield neuroprotection in preclinical stroke models by secreting extracellular vesicles (EVs). The neuroprotective cargo of EVs, however, has not yet been identified. To investigate such cargo and its underlying mechanism, primary neurons were exposed to oxygen‐g...

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Detalles Bibliográficos
Publicado en:J Extracell Vesicles
Autores principales: Kuang, Yaoyun, Zheng, Xuan, Zhang, Lin, Ai, Xiaoyu, Venkataramani, Vivek, Kilic, Ertugrul, Hermann, Dirk M., Majid, Arshad, Bähr, Mathias, Doeppner, Thorsten R.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710129/
https://ncbi.nlm.nih.gov/pubmed/33304476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jev2.12024
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