Lithium modulates miR‐1906 levels of mesenchymal stem cell‐derived extracellular vesicles contributing to poststroke neuroprotection by toll‐like receptor 4 regulation

Lithium is neuroprotective in preclinical stroke models. In addition to that, poststroke neuroregeneration is stimulated upon transplantation of mesenchymal stem cells (MSCs). Preconditioning of MSCs with lithium further enhances the neuroregenerative potential of MSCs, which act by secreting extrac...

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Detalhes bibliográficos
Publicado no:Stem Cells Transl Med
Main Authors: Haupt, Matteo, Zheng, Xuan, Kuang, Yaoyun, Lieschke, Simone, Janssen, Lisa, Bosche, Bert, Jin, Fengyan, Hein, Katharina, Kilic, Ertugrul, Venkataramani, Vivek, Hermann, Dirk M., Bähr, Mathias, Doeppner, Thorsten R.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Cell Based Drug Development, Screening, and Toxicology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7900596/
https://ncbi.nlm.nih.gov/pubmed/33146943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.20-0086
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