TAT-Hsp70 induces neuroprotection against stroke via anti-inflammatory actions providing appropriate cellular microenvironment for transplantation of neural precursor cells

Heat-shock protein 70 (Hsp70) protects against cerebral ischemia, which is attributed to its chaperone activity. However, recent reports also describe pro-inflammatory actions of Hsp70 via activation of Toll-like receptors (TLR). Using membrane-permeable transactivator of transcription (TAT)-Hsp70,...

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Detalhes bibliográficos
Main Authors: Doeppner, Thorsten R, Kaltwasser, Britta, Fengyan, Jin, Hermann, Dirk M, Bähr, Mathias
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824176/
https://ncbi.nlm.nih.gov/pubmed/23881248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.126
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