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Nitroalkanes as Versatile Nucleophiles for Enzymatic Synthesis of Noncanonical Amino Acids

C–C bond-forming reactions often require nucleophilic carbon species rarely compatible with aqueous reaction media, thus restricting their appearance in biocatalysis. Here we report the use of nitroalkanes as a structurally versatile class of nucleophilic substrates for C–C bond formation catalyzed...

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Detalhes bibliográficos
Publicado no:ACS Catal
Main Authors: Romney, David K., Sarai, Nicholas S., Arnold, Frances H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7709965/
https://ncbi.nlm.nih.gov/pubmed/33274115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.9b02089
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