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Expanding the Versatility of Microbial Transglutaminase Using α-Effect Nucleophiles as Noncanonical Substrates

The substrate promiscuity of microbial transglutaminase (mTG) has been exploited in various applications in biotechnology, in particular for the attachment of alkyl amines to glutamine-containing peptides and proteins. Here we expand the substrate repertoire to include hydrazines, hydrazides, and al...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Angew Chem Int Ed Engl
Egile Nagusiak: Chio, Tak Ian, Demestichas, Breanna R., Brems, Brittany M., Bane, Susan L., Tumey, L. Nathan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415582/
https://ncbi.nlm.nih.gov/pubmed/32268004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202001830
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