Atypical UV Photoproducts Induce Non-canonical Mutation Classes Associated with Driver Mutations in Melanoma

Somatic mutations in skin cancers and other ultraviolet (UV)-exposed cells are typified by C>T and CC>TT substitutions at dipyrimidine sequences; however, many oncogenic “driver” mutations in melanoma do not fit this UV signature. Here, we use genome sequencing to characterize mutations in yea...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Cell Rep
Главные авторы: Laughery, Marian F., Brown, Alexander J., Bohm, Kaitlynne A., Sivapragasam, Smitha, Morris, Haley S., Tchmola, Mila, Washington, Angelica D., Mitchell, Debra, Mather, Stephen, Malc, Ewa P., Mieczkowski, Piotr A., Roberts, Steven A., Wyrick, John J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7709870/
https://ncbi.nlm.nih.gov/pubmed/33207206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108401
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы