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The Role of Complement in the Mechanism of Action of Therapeutic Anti-Cancer mAbs
Unconjugated anti-cancer IgG1 monoclonal antibodies (mAbs) activate antibody-dependent cellular cytotoxicity (ADCC) by natural killer (NK) cells and antibody-dependent cellular phagocytosis (ADCP) by macrophages, and these activities are thought to be important mechanisms of action for many of these...
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| Publicat a: | Antibodies (Basel) |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7709112/ https://ncbi.nlm.nih.gov/pubmed/33126570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antib9040058 |
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