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How Do mAbs Make Use of Complement to Kill Cancer Cells? The Role of Ca(2+)

We examined the kinetics and mechanisms by which monoclonal antibodies (mAbs) utilize complement to rapidly kill targeted cancer cells. Based on results from flow cytometry, confocal microscopy and high-resolution digital imaging experiments, the general patterns which have emerged reveal cytotoxic...

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Detalhes bibliográficos
Publicado no:Antibodies (Basel)
Main Authors: Taylor, Ronald P., Lindorfer, Margaret A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7551823/
https://ncbi.nlm.nih.gov/pubmed/32899722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antib9030045
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