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Accelerated Approval or Risk Reduction? How Response Biomarkers Advance Therapeutics through Clinical Trials in Cystic Fibrosis

Progress in the development of new therapies for cystic fibrosis (CF) has benefitted from therapeutically responsive biomarkers to streamline drug development. Paradoxically, these response biomarkers have proven to be essential even in the presence of data demonstrating a lack of correlation with c...

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Bibliografiska uppgifter
I publikationen:Trends Mol Med
Huvudupphovsmän: Mayer-Hamblett, N, VanDevanter, DR
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708517/
https://ncbi.nlm.nih.gov/pubmed/32868171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2020.08.002
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