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Accelerated Approval or Risk Reduction? How Response Biomarkers Advance Therapeutics through Clinical Trials in Cystic Fibrosis

Progress in the development of new therapies for cystic fibrosis (CF) has benefitted from therapeutically responsive biomarkers to streamline drug development. Paradoxically, these response biomarkers have proven to be essential even in the presence of data demonstrating a lack of correlation with c...

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書目詳細資料
發表在:Trends Mol Med
Main Authors: Mayer-Hamblett, N, VanDevanter, DR
格式: Artigo
語言:Inglês
出版: 2020
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708517/
https://ncbi.nlm.nih.gov/pubmed/32868171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2020.08.002
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