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Identification of potential TNF-α inhibitors: from in silico to in vitro studies

Tumor Necrosis Factor Alpha (TNF-α) is a pleiotropic pro-inflammatory cytokine. It act as central biological regulator in critical immune functions, but its dysregulation has been linked with a number of diseases. Inhibition of TNF-α has considerable therapeutic potential for diseases such as cancer...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zia, Komal, Ashraf, Sajda, Jabeen, Almas, Saeed, Maria, Nur-e-Alam, Mohammad, Ahmed, Sarfaraz, Al-Rehaily, Adnan J., Ul-Haq, Zaheer
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708426/
https://ncbi.nlm.nih.gov/pubmed/33262408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77750-3
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