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3D-QSAR Studies on Barbituric Acid Derivatives as Urease Inhibitors and the Effect of Charges on the Quality of a Model

Urease enzyme (EC 3.5.1.5) has been determined as a virulence factor in pathogenic microorganisms that are accountable for the development of different diseases in humans and animals. In continuance of our earlier study on the helicobacter pylori urease inhibition by barbituric acid derivatives, 3D-...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Ul-Haq, Zaheer, Ashraf, Sajda, Al-Majid, Abdullah Mohammed, Barakat, Assem
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881483/
https://ncbi.nlm.nih.gov/pubmed/27144563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17050657
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