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3D-QSAR Studies on Barbituric Acid Derivatives as Urease Inhibitors and the Effect of Charges on the Quality of a Model

Urease enzyme (EC 3.5.1.5) has been determined as a virulence factor in pathogenic microorganisms that are accountable for the development of different diseases in humans and animals. In continuance of our earlier study on the helicobacter pylori urease inhibition by barbituric acid derivatives, 3D-...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ul-Haq, Zaheer, Ashraf, Sajda, Al-Majid, Abdullah Mohammed, Barakat, Assem
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881483/
https://ncbi.nlm.nih.gov/pubmed/27144563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17050657
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