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3D-QSAR Studies on Barbituric Acid Derivatives as Urease Inhibitors and the Effect of Charges on the Quality of a Model

Urease enzyme (EC 3.5.1.5) has been determined as a virulence factor in pathogenic microorganisms that are accountable for the development of different diseases in humans and animals. In continuance of our earlier study on the helicobacter pylori urease inhibition by barbituric acid derivatives, 3D-...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Ul-Haq, Zaheer, Ashraf, Sajda, Al-Majid, Abdullah Mohammed, Barakat, Assem
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881483/
https://ncbi.nlm.nih.gov/pubmed/27144563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17050657
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