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Quantum mechanics and 3D-QSAR studies on thienopyridine analogues: inhibitors of IKKβ

Inhibitor of kappa B kinase subunit β (IKKβ) is a main regulator of nuclear factor kappa B (NF-κB) and has received considerable attention as an attractive therapeutic target for the treatment of lung cancer or other inflammatory disease. A group of diversified thienopyridine derivatives exhibited a...

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Podrobná bibliografie
Vydáno v:Heliyon
Hlavní autoři: Ul-Haq, Zaheer, Khan, Alamgir, Ashraf, Sajda, Morales-Bayuelo, Alejandro
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7298411/
https://ncbi.nlm.nih.gov/pubmed/32566780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2020.e04125
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