MAFB and MAF Transcription Factors as Macrophage Checkpoints for COVID-19 Severity

Defective IFN production and exacerbated inflammatory and pro-fibrotic responses are hallmarks of SARS-CoV-2 infection in severe COVID-19. Based on these hallmarks, and considering the pivotal role of macrophages in COVID-19 pathogenesis, we hypothesize that the transcription factors MAFB and MAF cr...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Front Immunol
मुख्य लेखकों: Vega, Miguel A., Simón-Fuentes, Miriam, González de la Aleja, Arturo, Nieto, Concha, Colmenares, María, Herrero, Cristina, Domínguez-Soto, Ángeles, Corbí, Ángel L.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Frontiers Media S.A. 2020
विषय:
Immunology
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708330/
https://ncbi.nlm.nih.gov/pubmed/33312178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.603507
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