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MAFB and MAF Transcription Factors as Macrophage Checkpoints for COVID-19 Severity

Defective IFN production and exacerbated inflammatory and pro-fibrotic responses are hallmarks of SARS-CoV-2 infection in severe COVID-19. Based on these hallmarks, and considering the pivotal role of macrophages in COVID-19 pathogenesis, we hypothesize that the transcription factors MAFB and MAF cr...

詳細記述

保存先:
書誌詳細
出版年:Front Immunol
主要な著者: Vega, Miguel A., Simón-Fuentes, Miriam, González de la Aleja, Arturo, Nieto, Concha, Colmenares, María, Herrero, Cristina, Domínguez-Soto, Ángeles, Corbí, Ángel L.
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708330/
https://ncbi.nlm.nih.gov/pubmed/33312178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.603507
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