Granzyme B Expression in Visceral Adipose Tissue Associates With Local Inflammation and Glyco-Metabolic Alterations in Obesity

Granzyme B (GrB) is a serine protease produced by immune and non-immune cells, able to promote multiple processes, like apoptosis, inflammation, extracellular matrix remodeling and fibrosis. GrB expression in visceral adipose tissue (VAT) was associated with tissue damage, local inflammation and ins...

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Publicat a:Front Immunol
Autors principals: Cimini, Flavia Agata, Barchetta, Ilaria, Ceccarelli, Valentina, Chiappetta, Caterina, Di Biasio, Alberto, Bertoccini, Laura, Sentinelli, Federica, Leonetti, Frida, Silecchia, Gianfranco, Di Cristofano, Claudio, Baroni, Marco Giorgio, Velotti, Francesca, Cavallo, Maria Gisella
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708321/
https://ncbi.nlm.nih.gov/pubmed/33312176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.589188
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