Granzyme B Expression in Visceral Adipose Tissue Associates With Local Inflammation and Glyco-Metabolic Alterations in Obesity

Granzyme B (GrB) is a serine protease produced by immune and non-immune cells, able to promote multiple processes, like apoptosis, inflammation, extracellular matrix remodeling and fibrosis. GrB expression in visceral adipose tissue (VAT) was associated with tissue damage, local inflammation and ins...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Cimini, Flavia Agata, Barchetta, Ilaria, Ceccarelli, Valentina, Chiappetta, Caterina, Di Biasio, Alberto, Bertoccini, Laura, Sentinelli, Federica, Leonetti, Frida, Silecchia, Gianfranco, Di Cristofano, Claudio, Baroni, Marco Giorgio, Velotti, Francesca, Cavallo, Maria Gisella
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708321/
https://ncbi.nlm.nih.gov/pubmed/33312176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.589188
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