INDEL detection, the ‘Achilles heel’ of precise genome editing: a survey of methods for accurate profiling of gene editing induced indels

Advances in genome editing technologies have enabled manipulation of genomes at the single base level. These technologies are based on programmable nucleases (PNs) that include meganucleases, zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs) and Clustered Regular...

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Bibliografiska uppgifter
I publikationen:Nucleic Acids Res
Huvudupphovsmän: Bennett, Eric Paul, Petersen, Bent Larsen, Johansen, Ida Elisabeth, Niu, Yiyuan, Yang, Zhang, Chamberlain, Christopher Aled, Met, Özcan, Wandall, Hans H, Frödin, Morten
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2020
Ämnen:
Survey and Summary
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708060/
https://ncbi.nlm.nih.gov/pubmed/33170255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa975
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