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INDEL detection, the ‘Achilles heel’ of precise genome editing: a survey of methods for accurate profiling of gene editing induced indels

Advances in genome editing technologies have enabled manipulation of genomes at the single base level. These technologies are based on programmable nucleases (PNs) that include meganucleases, zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs) and Clustered Regular...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Bennett, Eric Paul, Petersen, Bent Larsen, Johansen, Ida Elisabeth, Niu, Yiyuan, Yang, Zhang, Chamberlain, Christopher Aled, Met, Özcan, Wandall, Hans H, Frödin, Morten
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708060/
https://ncbi.nlm.nih.gov/pubmed/33170255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa975
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