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INDEL detection, the ‘Achilles heel’ of precise genome editing: a survey of methods for accurate profiling of gene editing induced indels

Advances in genome editing technologies have enabled manipulation of genomes at the single base level. These technologies are based on programmable nucleases (PNs) that include meganucleases, zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs) and Clustered Regular...

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Publicat a:Nucleic Acids Res
Autors principals: Bennett, Eric Paul, Petersen, Bent Larsen, Johansen, Ida Elisabeth, Niu, Yiyuan, Yang, Zhang, Chamberlain, Christopher Aled, Met, Özcan, Wandall, Hans H, Frödin, Morten
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708060/
https://ncbi.nlm.nih.gov/pubmed/33170255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa975
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