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Sexually dimorphic DNA damage responses and mutation avoidance in the mouse germline

Germ cells specified during fetal development form the foundation of the mammalian germline. These primordial germ cells (PGCs) undergo rapid proliferation, yet the germline is highly refractory to mutation accumulation compared with somatic cells. Importantly, while the presence of endogenous or ex...

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Bibliografski detalji
Izdano u:Genes Dev
Glavni autori: Bloom, Jordana C., Schimenti, John C.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7706705/
https://ncbi.nlm.nih.gov/pubmed/33184219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.341602.120
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