STAT3 inhibition sensitizes colorectal cancer to chemoradiotherapy in vitro and in vivo

Increased activity of signal transducer and activator of transcription 3 (STAT3) is common in human malignancies, including colorectal cancers (CRCs). We have recently reported that STAT3 gene expression correlates with resistance of CRC cell lines to 5-fluorouracil (5-FU)-based chemoradiotherapy (C...

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Udgivet i:Int J Cancer
Main Authors: Spitzner, Melanie, Roesler, Birte, Bielfeld, Christian, Emons, Georg, Gaedcke, Jochen, Wolff, Hendrik A., Rave-Fränk, Margret, Kramer, Frank, Beissbarth, Tim, Kitz, Julia, Wienands, Jürgen, Ghadimi, B. Michael, Ebner, Reinhard, Ried, Thomas, Grade, Marian
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7706351/
https://ncbi.nlm.nih.gov/pubmed/23934972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.28429
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