Aurora-B knockdown inhibits osteosarcoma metastasis by inducing autophagy via the mTOR/ULK1 pathway

BACKGROUND: Autophagy plays an essential role in metastasis of malignancies. Although our studies showed that Aurora-B facilitate pulmonary metastasis in OS, the mechanism of Aurora-B kinase on autophagy and metastasis in OS has not been explored. METHODS: Clinical-pathological parameters and follow...

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Bibliografiske detaljer
Udgivet i:Cancer Cell Int
Main Authors: Wu, Xin, Liu, Jia-ming, Song, Hong-hai, Yang, Qi-kun, Ying, Hui, Tong, Wei-lai, Zhou, Yang, Liu, Zhi-li
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Primary Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7706191/
https://ncbi.nlm.nih.gov/pubmed/33292257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01674-1
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