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Changed reactivity of secondary hydroxy groups in C8-modified adenosine – lessons learned from silylation

Synthesis of site-specifically modified oligonucleotides has become a major tool for RNA structure and function studies. Reporter groups or specific functional entities are required to be attached at a pre-defined site of the oligomer. An attractive strategy is the incorporation of suitably function...

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Bibliografiska uppgifter
I publikationen:Beilstein J Org Chem
Huvudupphovsmän: Frommer, Jennifer, Müller, Sabine
Materialtyp: Artigo
Språk:Inglês
Publicerad: Beilstein-Institut 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7705864/
https://ncbi.nlm.nih.gov/pubmed/33299483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.16.234
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