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Changed reactivity of secondary hydroxy groups in C8-modified adenosine – lessons learned from silylation
Synthesis of site-specifically modified oligonucleotides has become a major tool for RNA structure and function studies. Reporter groups or specific functional entities are required to be attached at a pre-defined site of the oligomer. An attractive strategy is the incorporation of suitably function...
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| Publicat a: | Beilstein J Org Chem |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Beilstein-Institut
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7705864/ https://ncbi.nlm.nih.gov/pubmed/33299483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.16.234 |
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