Simultaneous profiling of chromatin accessibility and methylation on human cell lines with nanopore sequencing

Probing epigenetic features on DNA has tremendous potential to advance our understanding of the phased epigenome. In this study, we use nanopore sequencing to evaluate CpG methylation and chromatin accessibility simultaneously on long strands of DNA by applying GpC methyltransferase to exogenously l...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Methods
Main Authors: Lee, Isac, Razaghi, Roham, Gilpatrick, Timothy, Molnar, Michael, Gershman, Ariel, Sadowski, Norah, Sedlazeck, Fritz J., Hansen, Kasper D., Simpson, Jared T., Timp, Winston
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7704922/
https://ncbi.nlm.nih.gov/pubmed/33230324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-020-01000-7
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados