De novo induction of lineage plasticity from human prostate luminal epithelial cells by activated AKT1 and c-Myc

Neuroendocrine prostate cancer (NEPC) is an aggressive variant of prostate cancer that either develops de novo or arises from prostate adenocarcinoma as a result of treatment resistance. Although the prostate basal cells have been shown to directly generate tumor cells with neuroendocrine features w...

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Vydáno v:Oncogene
Hlavní autoři: Kwon, Oh-Joon, Zhang, Li, Jia, Deyong, Zhou, Zhicheng, Li, Zhouyihan, Haffner, Michael, Lee, John K, True, Lawrence, Morrissey, Colm, Xin, Li
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7704645/
https://ncbi.nlm.nih.gov/pubmed/33009488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01487-6
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