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Sox2 is necessary for androgen ablation-induced neuroendocrine differentiation from Pten null Sca-1(+) prostate luminal cells

Prostate adenocarcinoma undergoes neuroendocrine differentiation to acquire resistance toward anti-hormonal therapies. The underlying mechanisms have been investigated extensively, among which Sox2 has been shown to play a critical role. However, genetic evidence in mouse models for prostate cancer...

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Bibliografiske detaljer
Udgivet i:Oncogene
Main Authors: Kwon, Oh-Joon, Zhang, Li, Jia, Deyong, Xin, Li
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7796948/
https://ncbi.nlm.nih.gov/pubmed/33110232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01526-2
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