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Notch promotes tumor metastasis in a prostate-specific Pten-null mouse model
Although Notch signaling is deregulated in prostate cancer, the role of this pathway in disease development and progression is not fully understood. Here, we analyzed 2 human prostate cancer data sets and found that higher Notch signaling correlates with increased metastatic potential and worse dise...
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| 出版年: | J Clin Invest |
|---|---|
| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4922719/ https://ncbi.nlm.nih.gov/pubmed/27294523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI84637 |
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