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TERT promoter alterations could provide a solution for Peto’s paradox in rodents

Cancer is a genetic disease caused by changes in gene expression resulting from somatic mutations and epigenetic changes. Although the probability of mutations is proportional with cell number and replication cycles, large bodied species do not develop cancer more frequently than smaller ones. This...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Vedelek, Balázs, Maddali, Asha Kiran, Davenova, Nurgul, Vedelek, Viktor, Boros, Imre M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7704627/
https://ncbi.nlm.nih.gov/pubmed/33257697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77648-0
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