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TERT promoter alterations could provide a solution for Peto’s paradox in rodents

Cancer is a genetic disease caused by changes in gene expression resulting from somatic mutations and epigenetic changes. Although the probability of mutations is proportional with cell number and replication cycles, large bodied species do not develop cancer more frequently than smaller ones. This...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Vedelek, Balázs, Maddali, Asha Kiran, Davenova, Nurgul, Vedelek, Viktor, Boros, Imre M.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7704627/
https://ncbi.nlm.nih.gov/pubmed/33257697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77648-0
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