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Biological mechanisms and therapeutic relevance of the gasdermin family
Innate immunity enables host defense against pathogens and endogenous danger through inflammasomes, which are supramolecular complexes that recognize the threats and activate the immune response. Inflammasome activation often leads to pyroptosis, a highly inflammatory and lytic form of cell death, a...
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| Publicat a: | Mol Aspects Med |
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| Autor principal: | |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7704569/ https://ncbi.nlm.nih.gov/pubmed/32800355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mam.2020.100890 |
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