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Biological mechanisms and therapeutic relevance of the gasdermin family
Innate immunity enables host defense against pathogens and endogenous danger through inflammasomes, which are supramolecular complexes that recognize the threats and activate the immune response. Inflammasome activation often leads to pyroptosis, a highly inflammatory and lytic form of cell death, a...
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| Publicado no: | Mol Aspects Med |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7704569/ https://ncbi.nlm.nih.gov/pubmed/32800355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mam.2020.100890 |
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