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Mechanism and Regulation of Gasdermin-Mediated Cell Death

The innate immune system senses and responds to pathogens and endogenous damage through supramolecular protein complexes known as inflammasomes. Cytosolic inflammasome sensor proteins trigger inflammasome assembly on detection of infection and danger. Assembled inflammasomes activate a cascade of in...

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Détails bibliographiques
Publié dans:Cold Spring Harb Perspect Biol
Auteurs principaux: Xia, Shiyu, Hollingsworth, Louis Robert, Wu, Hao
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050592/
https://ncbi.nlm.nih.gov/pubmed/31451512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a036400
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