Cardiomyocyte Oga haploinsufficiency increases O-GlcNAcylation but hastens ventricular dysfunction following myocardial infarction

RATIONALE: The beta-O-linkage of N-acetylglucosamine (i.e., O-GlcNAc) to proteins is a pro-adaptive response to cellular insults. To this end, increased protein O-GlcNAcylation improves short-term survival of cardiomyocytes subjected to acute injury. This observation has been repeated by multiple gr...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:PLoS One
Main Authors: Dassanayaka, Sujith, Brittian, Kenneth R., Long, Bethany W., Higgins, Lauren A., Bradley, James A., Audam, Timothy N., Jurkovic, Andrea, Gumpert, Anna M., Harrison, Linda T., Hartyánszky, István, Perge, Péter, Merkely, Béla, Radovits, Tamás, Hanover, John A., Jones, Steven P.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2020
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7703924/
https://ncbi.nlm.nih.gov/pubmed/33253217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0242250
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